# Publications Search Within Results Search Within Results search ## 25 results Show filters filter\_alt Sort by Year of PublicationAlphabetical A-Z sort ## 25 results Download 25 citations download- [BibTeX](/node/723446/export?format=bibtex) - [EndNote X3 XML](/node/723446/export?format=endnote8) - [EndNote 7 XML](/node/723446/export?format=endnote7) - [Endnote tagged](/node/723446/export?format=tagged) - [Marc](/node/723446/export?format=marc) - [PubMedId](/node/723446/export?format=pubmed_id) - [RIS](/node/723446/export?format=ris) ### 2024 Alejandro Couce, Anurag Limdi, Melanie Magnan, Siân V. Owen, Cristina M. Herren, Richard E. Lenski, Olivier Tenaillon, and Michael Baym. 2024. “[Changing Fitness Effects of Mutations through Long-Term Bacterial Evolution](/publications/changing-fitness-effects-mutations-through-long-term-bacterial-evolution)”. Science, 383, 6681, Pp. eadd1417. doi:10.1126/science.add1417 Alejandro Couce, Anurag Limdi, Melanie Magnan, Siân V. Owen, Cristina M. Herren, Richard E. Lenski, Olivier Tenaillon, and Michael Baym. 2024. “[Changing Fitness Effects of Mutations through Long-Term Bacterial Evolution](/publications/changing-fitness-effects-mutations-through-long-term-bacterial-evolution)”. Science, 383, 6681, Pp. eadd1417. doi:10.1126/science.add1417 - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://www.science.org/doi/abs/10.1126/science.add1417) The distribution of fitness effects of new mutations shapes evolution, but it is challenging to observe how it changes as organisms adapt. Using Escherichia coli lineages spanning 50,000 generations of evolution, we quantify the fitness effects of... - [ descriptionPublisher's Version](https://www.science.org/doi/abs/10.1126/science.add1417) Natalia Quinones-Olvera, Siân V. Owen, Lucy M. McCully, Maximillian G. Marin, Eleanor A. Rand, Alice C. Fan, Oluremi J. Martins Dosumu, Kay Paul, Cleotilde E. Sanchez Castaño, Rachel Petherbridge, Jillian S. Paull, and Michael Baym. 2024. “[Diverse and Abundant Phages Exploit Conjugative Plasmids.](/publications/diverse-and-abundant-phages-exploit-conjugative-plasmids)”. Nature Communications, 15, 1, Pp. 3197. doi:10.1038/s41467-024-47416-z Natalia Quinones-Olvera, Siân V. Owen, Lucy M. McCully, Maximillian G. Marin, Eleanor A. Rand, Alice C. Fan, Oluremi J. Martins Dosumu, Kay Paul, Cleotilde E. Sanchez Castaño, Rachel Petherbridge, Jillian S. Paull, and Michael Baym. 2024. “[Diverse and Abundant Phages Exploit Conjugative Plasmids.](/publications/diverse-and-abundant-phages-exploit-conjugative-plasmids)”. Nature Communications, 15, 1, Pp. 3197. doi:10.1038/s41467-024-47416-z - add\_circle do\_not\_disturb\_on Abstract Phages exert profound evolutionary pressure on bacteria by interacting with receptors on the cell surface to initiate infection. While the majority of phages use chromosomally encoded cell surface structures as receptors, plasmid-dependent phages exploit... ### 2023 Charles L. Dulberger, Carlos A. Guerrero-Bustamante, Siân V. Owen, Sean Wilson, Michael G. Wuo, Rebecca A. Garlena, Lexi A. Serpa, Daniel A. Russell, Junhao Zhu, Ben J. Braunecker, Georgia R. Squyres, Michael Baym, Laura L. Kiessling, Ethan C. Garner, Eric J. Rubin, and Graham F. Hatfull. 2023. “[Mycobacterial Nucleoid-Associated Protein Lsr2 Is Required for Productive Mycobacteriophage Infection](/publications/mycobacterial-nucleoid-associated-protein-lsr2-required-productive)”. Nature Microbiology, Pp. 1–16. doi:10.1038/s41564-023-01333-x Charles L. Dulberger, Carlos A. Guerrero-Bustamante, Siân V. Owen, Sean Wilson, Michael G. Wuo, Rebecca A. Garlena, Lexi A. Serpa, Daniel A. Russell, Junhao Zhu, Ben J. Braunecker, Georgia R. Squyres, Michael Baym, Laura L. Kiessling, Ethan C. Garner, Eric J. Rubin, and Graham F. Hatfull. 2023. “[Mycobacterial Nucleoid-Associated Protein Lsr2 Is Required for Productive Mycobacteriophage Infection](/publications/mycobacterial-nucleoid-associated-protein-lsr2-required-productive)”. Nature Microbiology, Pp. 1–16. doi:10.1038/s41564-023-01333-x - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://www.nature.com/articles/s41564-023-01333-x) Mycobacteriophages are a diverse group of viruses infecting Mycobacterium with substantial therapeutic potential. However, as this potential becomes realized, the molecular details of phage infection and mechanisms of resistance remain ill-defined. Here... - [ descriptionPublisher's Version](https://www.nature.com/articles/s41564-023-01333-x) Akos Nyerges, Svenja Vinke, Regan Flynn, Siân V. Owen, Eleanor A. Rand, Bogdan Budnik, Eric Keen, Kamesh Narasimhan, Jorge A. Marchand, Maximilien Baas-Thomas, Min Liu, Kangming Chen, Anush Chiappino-Pepe, Fangxiang Hu, Michael Baym, and George M. Church. 2023. “[A Swapped Genetic Code Prevents Viral Infections and Gene Transfer](/publications/swapped-genetic-code-prevents-viral-infections-and-gene-transfer)”. Nature, 615, 7953, Pp. 720–727. doi:10.1038/s41586-023-05824-z Akos Nyerges, Svenja Vinke, Regan Flynn, Siân V. Owen, Eleanor A. Rand, Bogdan Budnik, Eric Keen, Kamesh Narasimhan, Jorge A. Marchand, Maximilien Baas-Thomas, Min Liu, Kangming Chen, Anush Chiappino-Pepe, Fangxiang Hu, Michael Baym, and George M. Church. 2023. “[A Swapped Genetic Code Prevents Viral Infections and Gene Transfer](/publications/swapped-genetic-code-prevents-viral-infections-and-gene-transfer)”. Nature, 615, 7953, Pp. 720–727. doi:10.1038/s41586-023-05824-z - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://www.nature.com/articles/s41586-023-05824-z) Engineering the genetic code of an organism has been proposed to provide a firewall from natural ecosystems by preventing viral infections and gene transfer1–6. However, numerous viruses and mobile genetic elements encode parts of the translational... - [ descriptionPublisher's Version](https://www.nature.com/articles/s41586-023-05824-z) ### 2022 Leonard Koolman, Reenesh Prakash, Yohane Diness, Chisomo Msefula, Tonney S. Nyirenda, Franziska Olgemoeller, Paul Wigley, Blanca Perez-Sepulveda, Jay C. D. Hinton, Siân V. Owen, Nicholas A. Feasey, Philip M. Ashton, and Melita A. Gordon. 2022. “[Case-Control Investigation of Invasive Salmonella Disease in Malawi Reveals No Evidence of Environmental or Animal Transmission of Invasive Strains, and Supports Human to Human Transmission](/publications/case-control-investigation-invasive-salmonella-disease-malawi-reveals-no)”. PLOS Neglected Tropical Diseases, 16, 12, Pp. 1-17. doi:10.1371/journal.pntd.0010982 Leonard Koolman, Reenesh Prakash, Yohane Diness, Chisomo Msefula, Tonney S. Nyirenda, Franziska Olgemoeller, Paul Wigley, Blanca Perez-Sepulveda, Jay C. D. Hinton, Siân V. Owen, Nicholas A. Feasey, Philip M. Ashton, and Melita A. Gordon. 2022. “[Case-Control Investigation of Invasive Salmonella Disease in Malawi Reveals No Evidence of Environmental or Animal Transmission of Invasive Strains, and Supports Human to Human Transmission](/publications/case-control-investigation-invasive-salmonella-disease-malawi-reveals-no)”. PLOS Neglected Tropical Diseases, 16, 12, Pp. 1-17. doi:10.1371/journal.pntd.0010982 - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://doi.org/10.1371/journal.pntd.0010982) Background Invasive Salmonella infections cause significant morbidity and mortality in Sub-Saharan Africa. However, the routes of transmission are uncertain. We conducted a case-control study of index-case and geographically-matched control households in... - [ descriptionPublisher's Version](https://doi.org/10.1371/journal.pntd.0010982) Sanne Wolput, Angela Makumi, Laura Wicke, Leonard Bäcker, William Cenens, Yves Briers, Nicolas Wenner, Siân Owen, Jay CD Hinton, Rob Lavigne, and others. 2022. “[Transcriptional Organization of the Salmonella Typhimurium Phage P22 Pid ORFan Locus](/publications/transcriptional-organization-salmonella-typhimurium-phage-p22-pid-orfan-locus)”. International Journal of Molecular Sciences, 23, 3, Pp. 1253 Sanne Wolput, Angela Makumi, Laura Wicke, Leonard Bäcker, William Cenens, Yves Briers, Nicolas Wenner, Siân Owen, Jay CD Hinton, Rob Lavigne, and others. 2022. “[Transcriptional Organization of the Salmonella Typhimurium Phage P22 Pid ORFan Locus](/publications/transcriptional-organization-salmonella-typhimurium-phage-p22-pid-orfan-locus)”. International Journal of Molecular Sciences, 23, 3, Pp. 1253 Justin Silpe, Joel WH Wong, Siân Owen, Michael Baym, and Emily P. Balskus. 2022. “[The Bacterial Toxin Colibactin Triggers Prophage Induction](/publications/bacterial-toxin-colibactin-triggers-prophage-induction)”. Nature, 603, 7900, Pp. 315–320 Justin Silpe, Joel WH Wong, Siân Owen, Michael Baym, and Emily P. Balskus. 2022. “[The Bacterial Toxin Colibactin Triggers Prophage Induction](/publications/bacterial-toxin-colibactin-triggers-prophage-induction)”. Nature, 603, 7900, Pp. 315–320 Anurag Limdi, Siân Owen, Cristina Herren, Richard Lenski, and Michael Baym. 2022. “[Parallel Changes in Gene Essentiality over 50,000 Generations of Evolution](/publications/parallel-changes-gene-essentiality-over-50000-generations-evolution)”. BioRxiv Anurag Limdi, Siân Owen, Cristina Herren, Richard Lenski, and Michael Baym. 2022. “[Parallel Changes in Gene Essentiality over 50,000 Generations of Evolution](/publications/parallel-changes-gene-essentiality-over-50000-generations-evolution)”. BioRxiv Akos Nyerges, Svenja Vinke, Regan Flynn, Siân V. Owen, Eleanor A. Rand, Bogdan Budnik, Eric Keen, Kamesh Narasimhan, Jorge A. Marchand, Maximilien Baas-Thomas, Min Liu, Kangming Chen, Anush Chiappino-Pepe, Fangxiang Hu, Michael Baym, and George M. Church. 2022. “[Swapped Genetic Code Blocks Viral Infections and Gene Transfer](/publications/swapped-genetic-code-blocks-viral-infections-and-gene-transfer)”. BioRxiv. doi:10.1101/2022.07.08.499367 Akos Nyerges, Svenja Vinke, Regan Flynn, Siân V. Owen, Eleanor A. Rand, Bogdan Budnik, Eric Keen, Kamesh Narasimhan, Jorge A. Marchand, Maximilien Baas-Thomas, Min Liu, Kangming Chen, Anush Chiappino-Pepe, Fangxiang Hu, Michael Baym, and George M. Church. 2022. “[Swapped Genetic Code Blocks Viral Infections and Gene Transfer](/publications/swapped-genetic-code-blocks-viral-infections-and-gene-transfer)”. BioRxiv. doi:10.1101/2022.07.08.499367 - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://www.biorxiv.org/content/early/2022/07/10/2022.07.08.499367) Removing cellular transfer RNAs (tRNAs), making their cognate codons unreadable, creates a genetic firewall that prevents viral replication and horizontal gene transfer. However, numerous viruses and mobile genetic elements encode parts of the... - [ descriptionPublisher's Version](https://www.biorxiv.org/content/early/2022/07/10/2022.07.08.499367) ### 2021 Siân V. Owen*, Nicolas Wenner*, Charles L. Dulberger, Ella V. Rodwell, Arthur Bowers-Barnard, Natalia Quinones-Olvera, Daniel J. Rigden, Eric J. Rubin, Ethan C. Garner, Michael Baym, and Jay C. D. Hinton. 2021. “[Prophages Encode Phage-Defense Systems With Cognate Self-Immunity](/publications/prophages-encode-phage-defense-systems-cognate-self-immunity)”. Cell Host & Microbe. doi:https://doi.org/10.1016/j.chom.2021.09.002 Siân V. Owen*, Nicolas Wenner*, Charles L. Dulberger, Ella V. Rodwell, Arthur Bowers-Barnard, Natalia Quinones-Olvera, Daniel J. Rigden, Eric J. Rubin, Ethan C. Garner, Michael Baym, and Jay C. D. Hinton. 2021. “[Prophages Encode Phage-Defense Systems With Cognate Self-Immunity](/publications/prophages-encode-phage-defense-systems-cognate-self-immunity)”. Cell Host & Microbe. doi:https://doi.org/10.1016/j.chom.2021.09.002 - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://www.sciencedirect.com/science/article/pii/S1931312821004182) Summary Temperate phages are pervasive in bacterial genomes, existing as vertically inherited islands termed prophages. Prophages are vulnerable to predation of their host bacterium by exogenous phages. Here, we identify BstA, a family of prophage-encoded... - [ descriptionPublisher's Version](https://www.sciencedirect.com/science/article/pii/S1931312821004182) Siân Owen, Blanca Perez-Sepulveda, and Evelien Adriaenssens. 2021. “[Detection of Bacteriophages: Sequence-Based Systems](/publications/detection-bacteriophages-sequence-based-systems-0)”. Bacteriophages: Biology, Technology, Therapy, Pp. 621–644 Siân Owen, Blanca Perez-Sepulveda, and Evelien Adriaenssens. 2021. “[Detection of Bacteriophages: Sequence-Based Systems](/publications/detection-bacteriophages-sequence-based-systems-0)”. Bacteriophages: Biology, Technology, Therapy, Pp. 621–644 ### 2020 Jared D. Honeycutt, Nicolas Wenner, Yan Li, Susan M. Brewer, Liliana M. Massis, Sky W. Brubaker, Phoom Chairatana, Siân V. Owen, Rocío Canals, Jay C. D. Hinton, and Denise M. Monack. 2020. “[Genetic Variation in the MacAB-TolC Efflux Pump Influences Pathogenesis of Invasive Salmonella Isolates from Africa](/publications/genetic-variation-macab-tolc-efflux-pump-influences-pathogenesis-invasive)”. PLOS Pathogens, 16, 8, Pp. 1-30. doi:10.1371/journal.ppat.1008763 Jared D. Honeycutt, Nicolas Wenner, Yan Li, Susan M. Brewer, Liliana M. Massis, Sky W. Brubaker, Phoom Chairatana, Siân V. Owen, Rocío Canals, Jay C. D. Hinton, and Denise M. Monack. 2020. “[Genetic Variation in the MacAB-TolC Efflux Pump Influences Pathogenesis of Invasive Salmonella Isolates from Africa](/publications/genetic-variation-macab-tolc-efflux-pump-influences-pathogenesis-invasive)”. PLOS Pathogens, 16, 8, Pp. 1-30. doi:10.1371/journal.ppat.1008763 - add\_circle do\_not\_disturb\_on Abstract - [ descriptionPublisher's Version](https://doi.org/10.1371/journal.ppat.1008763) Author summary Salmonella Typhimurium will generally cause acute gut infections in humans. However, S. Typhimurium strains causing severe, systemic infections have emerged in sub-Saharan Africa and are phylogenetically distinct from other S. Typhimurium... - [ descriptionPublisher's Version](https://doi.org/10.1371/journal.ppat.1008763) - Previous page chevron\_left - [1](?page=0 "Current page") - [2](?page=1 "Go to page 2") - [3](?page=2 "Go to page 3") - [ Next page chevron\_right ](?page=1 "Go to next page")